Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep74 | Adrenal and Cardiovascular Endocrinology | ECE2022

Magnetic iron oxide nanoparticles for the delivery of thermal therapy for the treatment of primary aldosteronism

Sorushanova Anna , Donlon Padraig , Covarrubias-Zambrano Obdulia , Covarrubias Jose , Varghese Sunitha , Owens Peter , O'Halloran Martin , Prakash Punit , Bossmann Stefan , Dennedy Michael Conall

To minimise damage to surrounding tissues, targeted delivery of therapeutics to the tumour is highly desirable, and the development of nanotechnology has shown promising results. Magnetic iron oxide nanoparticles (MIONPs) have been gaining traction over the years for applications such as drug delivery, molecular imaging and delivering hyperthermia for treatment of various cancers (1). MIONPs have great therapeutic potential as they can be produced in various sizes and shapes, ...

ea0090p552 | Adrenal and Cardiovascular Endocrinology | ECE2023

Non-specific uptake of magnetic iron oxide nanoparticles by Adrenocortical carcinoma and Endothelial cells

Sorushanova Anna , Donlon Padraig , Mullen Nathan , Covarrubias-Zambrano Obdulia , Covarrubias Jose , Varghese Sunitha , Hantel Constanza , Owens Peter , O'Halloran Martin , Prakash Punit , Bossman Stefan , Conall Dennedy Michael

Adrenocortical carcinoma is a rare malignant tumour that starts in the adrenal gland, accounting for 4% of all adrenal tumours. Functioning ACC can cause symptoms related to the overproduction of hormones and large tumours can press on nearby organs. Primary treatment for ACC tumour is surgery to remove the tumour, and may also include Chemotherapy or Radiation to stop the cancer cells from spreading. Therefore, more affective therapies for delivering therapeutics to the tumou...